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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1923L1 | ELA-14(human) acetate | ELA-14(human) acetate (1886973-05-2 free base) | Apelin receptor , Arrestin |
ELA-14(human) acetate is a fragment of ELA that binds to APJ, activates the Gαi1 and β-arrestin-2 signaling pathways, and induces receptor internalization similarly to its parent endogenous peptide. | |||
TP1923 | Elabela(19-32) | ELA-14 (human) | |
Potent apelin (APJ) receptor agonist (Ki = 0.93 nM). Bioactive fragment of ELA-32. Activates Gαi1 pathway and β-arrestin-2 recruitment. Reduces arterial pressure in rat hearts. Active in vivo. | |||
TP1922L1 | ELA-11 (human) acetate(1784687-32-6 free base) | Apelin receptor , Arrestin | |
ELA-11 (human) acetate high affinity apelin receptor agonist (Ki = 14 nM). Bioactive fragment of ELA-32. Inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro. | |||
T76053 | ELA-11(human) TFA | ||
ELA-11(human) TFA, a bioactive fragment of ELA-32, acts as a high-affinity apelin receptor agonist (K i =14 nM). It effectively inhibits forskolin-induced cAMP production and promotes β-arrestin recruitment in vitro, hig... |